October 2017 Edition. Volume XVII


PRFFNB Illustration 75pIn the latter third of the 20th century the modern specialty of spine care first began to  evolve.  A number of innovative concepts and associated procedures were the result of this.  Some of these therapies have not successfully withstood the test of time but others have remained in the treatment armamentarium because of their well-demonstrated continuum of safety and efficacy. The chronicle of how facet and medial branch injections and radio-frequency (RF) blocks came to be is a particularly intriguing tale known, but only to a few.


The modern era of interest in the facet (zygoapophyseal) joints came about when clinicians began to recognize that these structures were important sources of low back pain and resulting disability. It appears that Joel Goldthwait was the first to recognize this connection in 1911 (The Lumbosacral Articulation: an explanation of many cases of ‘lumbago,’ ‘sciatica,’ and ‘paraplegia.'” Boston Medical Surgical Journal 1911) followed soon after by Ralph Ghormley  in 1933 (Low Back Pain with Special Reference to the Articular Facets, with Presentation of An Operative Procedure.” Journal of American Medical Association 1933).

The credit for the first anatomic studies performed on the innervation of the facet joints goes to Professor Guy Lazorthes and his associates in Toulouse France, beginning in the 1950s (Lazorthes G, Gaubert J: L’innervation des articulations interapophysaires vertebrales, Comp Rend Assoc Anat 43:488-494, 1956).  Because his works were published only in French journals a number of decades passed before his contributions were appreciated by the English speaking medical world. The later work of Drs. Stanley Paris , Nikolai Bogduk, and others in the 1980s served to complement and confirm the original work of Lazorthes and to build a scientific basis for our present understanding and associated treatment of the “facet syndrome” as an important contributor to the etiology of low back pain in the world’s population.  

FacetParis200GIF DorRtGanglia200GIF

Dr. Paris is shown above studying the dorsal root complex of a cadaver.  In the drawing at right the green dot is on the dorsal ramus of the emerging dorsal nerve root ganglion.  The yellow dot shows the point at which this ramus the continues as extremely small A-delta and C-fiber branches which are actually thinner than a spider web strand which averages 4-5 µm (microns) .  These minute sensory nerves innervate the facet joints.  The medial branch of this complex is the typical target for  injections and permanent radio-frequency (RF) blocks; also referred to as “cauterizations”, “ablations”, and “neurolysis”. The task of attempting to make sense of all of this information fell to Professor William Kilkaldy-Willis at the University of Saskatoon, Saskatchewan, Canada who, on the basis of his personal research (Kirkaldy-Willis W et al. Pathology and Pathogenesis of Lumbar Spondylosis and Stenosis, Spine, Vol 3, No. 4, pp. 318-328, 1978) during the 1970s initiated the concept of  the “degenerative cascade”. Kirkaldy-Willis’ anatomic studies were soon confirmed by radiologists and clinicians who could then begin to visualize these same entities on computed tomographic scans (CT) and then on magnetic resonant imaging (MRI) studies.

FacetCTclam150GIF FacetK-Wclamshell150GIF  FacetCTDegen150GIF  FacetDegSpond150GIF

In the first of the illustrations above the arrows point to areas of the articular facet joint which have eroded and have  resulted in joint dysfunction as shown on this CT scan. In the second image the arrow points to a similar area of erosion in a pathologic specimen provided by Professor Kirkaldy-Willis.  The third image also shows facet joints with more advanced degenerative change which has led to a degenerative spondylolisthesis (last illustration) due to progressive degeneration of these facet joints.  When more advanced facet degeneration occurred it could create listhesis and lateral spinal stenosis, the most common cause for creation of the “failed back surgery syndrome”. It is important to point out that if the patient is a non-smoker the great majority of these patients, with appropriate non-surgical care go on to self-heal and to self-stabilize their spines.

In the late 1960s an Australian surgeon, W. E. Skyrmer Rees, first introduced the concept of treating facet related low back pain by surgically cutting the intertransverse ligament with a scalpel in order to section the dorsal ramus of a spinal nerve as a means of producing a sensory blockade and thus relieving back pain secondary to what has become called the “facet syndrome”.  The illustration shown below was drawn by Rees, in 1971, to illustrate how a “Beaver Eye Knife” (scalpel) was utilized to surgically section this intertransverse ligament and the dorsal ramus of the postganglionic segment of the spinal nerve.

FacetReesTech200GIFRees referred to his procedure as “dorsal root rhizolysis” and usually performed it on both sides.  Following publication of his work in the 1975 Medical Journal of Australia American neurosurgeon C. Norman Shealy visited Rees in Australia.

ShealyAlone200GIFShealy observed Rees’ procedures, and returned to the United States where he performed rhizolysis on a number of his own patients. He concluded that while the procedure seemed to have merit in producing pain relief it was certainly not minimally invasive and often produced significant subcutaneous hematomas.  Shealy’s previous experience with radio-frequency coagulating electrodes used to treat conditions such as trigeminal neuralgia led him to replace the Beaver scalpel with a radiofrequency electrode probe. Unfortunatlely, the term “rhizolysis’ (cutting a nerve) continues to be misused by some practitioners rather than the term “dennervation.”

It remained for some of Shealy’s neurosurgical colleagues to further refine this clinically valuable technique . A significant improvement was achieved when neurosurgeon Charles Ray (seen below), designed a trocar type electrode. At about this time, based on the anatomic studies of Paris and Bogduk, it became evident that a that a much more safe and selective procedure could be performed by simply cauterizing the medial branch of the dorsal nerve ramus at the base of the transverse process (providing a definitive [and safe] bony end-point) for the procedure.

Ray200GIFThis percutaneous approach replaced the need for of general anesthesia and allowed dennervation to be performed with “monitored anesthetic control” using local anesthesia and parenteral supplementation (i.e. Fentanyl and  Versed). At this point percutaneous radio-frequency facet blocks then became the “gold standard” for safety and efficacy. Initially this procedure was performed bilaterally and at multiple levels at one time by the pioneering neurosurgeons who developed it.

FacetRFproced200GIF FacetRFProbe200GIF PRFFNB Illustration

Shown above is a radiofrequency procedure in progress.  The Ray electrode (or other RF electrodes) are inserted percutaneously under fluoroscopic control and directed to the base of each transverse process, where a monitored RF coagulation lesion is produced.



The illustration to FacetSpiderWeb200GIFthe left demonstrates the standard neurosurgical target areas which were recommended for the  placement of the radiofrequency probe in the 1970’s.

The justification for lesion production being carried out bilaterally and at multiple sites had to do with the non-specific sensory input system of the facets which is similar to a spider’s web with the goal being to not to destroy the system but to block some of the “strands” as a means of cutting down on the system’s sensitivity. Some clinicians initially issued dire predictions that RF lesioning would produce “Charcot” joints (total denervation of a joint sometimes seen with syphilis or diabetes initially described by Jean-Martin Charcot, 1825-1893, Professor of Neurology at the University of Paris) or denervation of the paravertebral muscles.  Fortunately, there has been no evidence, over many years, that this occurs. Other dire predictions regarding significant have also not been borne out.  What has become evident is that the RF procedure, by decreasing the sensitivity of the A-Delta and C fiber facet “alarm system” has been most effective in relieving low back pain related to the facet “syndrome” and providing the opportunity of initiating a “window of opportunity” of better health habits (mainly cessation of smoking), appropriate exercise and daily health maintenance to allow for normal self-healing to occur..

The Burton Experience

The Burton Experience with percutaneous radio-frequency facet blocks began in the early 1972 when the Editor invited Norman Shealy to give a presentation on “Articular Nerve of Luschka, Rhizotomy for Back and Leg Pain” at Temple University Health Sciences Center in Philadelphia.  The term “Luschka” referred to German Anatomist Herbert von Luschka (1820-1875) who studied and described the uncovertebral (facet) joint. This usage became synonymous with the the term “zygoapophyseal joint.”

Following this symposium a Joint Study Group consisting of neurosurgeons Shealy, Prieto, Burton, and Long initiated an interinstutional trial of this procedure.  These clinical results were presented at the annual meeting of the American Association of Neurological Surgeons in Los Angeles in 1973.  In the Burton series the overall long-term procedure efficacy (3 year follow-up) was 67% (Burton CV: Percutaneous Radiofrequency Facet Denervation, Applied Neurophysiology, 39:80-86, 1977).  

Radiofrequency facet blocks are now, after almost half a century of clinical application, considered to be “well established” by the world spine specialist community.  They have, on the basis of a large population of clinical use, proven to be a valid and important, minimally invasive, low risk procedure for the well-selected patient with a “facet syndrome” when applied by experienced physicians using x-ray control.

Initially, many health healthcare insurers refused to pay for RF facet denervation because, over the years, there had never been a double-blind controlled clinical study. Remarkably, Nath et al actually performed such a randomized controlled study to confirm efficacy which was published in the Journal Spine in 2008 (Nath et al, Percutaneous Lumbar Zygoapophyseal (Facet) Joint Neurotomy Using Radiofrequency Current, in the Management of Chronic Low Back Pain, Spine, Vol. 33, No. 12, pp. 1291-1297, 2008).

PRFFNB Illustration 75pInitially RF facet blocks were always performed by neurosurgeons.  Once a high degree of safety and efficacy had been well demonstrated however “pain management” specialists entered upon the clinical scene and spine procedure oriented clinics specializing in percutaneous procedures began to pop up in most large communities throughout the U.S.  This has clearly now become “big business” particularly in regard to repeat epidural steroids and facet and medial branch injections and blocks for which there has evolved often shameful over utilization of health care.  Data presented at the North American Spine Society by Venu Akuthota, M.D., and associates  reviewing a database of 12 million to 14 million privately insured adults in the U.S.  found that a minority of the procedurists accounted for the majority of the procedures performed.  The range of procedures performed on a individual patient over the course of one year for epidural steroid injections was 1-51, for facet or medial branch blocks 1-135, and for radiofrequency medial branch ablations was 1-34.  In the Editor’s experience less than 5% of his patients ever required more than one repeat session of radiofrequency medial branch ablations.

While the neurosurgical experience documented that it was not unusual for patients to experience continued pain relief for many years following percutaneous RF Facet blocks (good results for as long as 20 years are known by the Editor).  The representation to patients that this is something which needs to be repeated, on a regular basis, throughout a patient’s life clearly reflects a point of view not substantiated by fact and inconsistent with the patient’s best interests.

Since the advent of treating back pain with minimally invasive percutaneous procedures there has evolved a new medical specialty, that of “Pain Management” typically practiced by anesthesiologists who earn their living by doing injections. It did not take long before pain management specialists began to control these injections and break them into multiple sessions rather than a single session. In today’s world 4 to 6 separate procedures have replaced the neurosurgeons one time treatment. Unfortunately, this is not improved clinical results. The beneficiaries appear to be the procedurists and not the patients or the health care system.

For the right patient, and if performed by the right specialist for the right reasons, radiofrequency facet blocks performed in the lumbar area, as well as in the  thoracic and cervical areas,  have been successful endeavors. In a study performed at Johns Hopkins by Steven Cohen in 2010 he pointed out that “if we just do the radiofrequency procedure first, we’re going to help more people and we’re going to save a lot of money.


Dorsal Root Rhizolysis and Dorsal Root Rhizotomy–  When Australian surgeon, W. E. Skyrmer Rees, first introduced the treating of low back pain emanating from the facet joints he actually intended to completely sever the dorsal nerve root with a scalpel.  He was the one, in the 1960s to coin the term “dorsal root rhizolysis“, which a correct description of what he was attempting to do.  The Latin “Rhiz” is translated “root”, referring to nerve root (i.e. dorsal nerve root) and “lysis” means “to cut”.  The term “otomy” is a bit more complex because it is used, in present medical lingo, to mean “to open”.  However,  “otomy” derives from the Greek work “tome”  meaning “to cut” and we are therefor back to meaning surgical division of of some or all the fibers of a nerve; not a minimally invasive percutaneous coagulation of small nerve fibers.

Articular Nerve of Luschka Rhizolysis– Term used by Shealy to describe his modification of the Rees procedure.  Rhizolysis is a misnomer and von Luschka never described a nerve associated with the uncovertebral joint.

Percutaneous Radiofrequency Facet Denervation
Term used originally by Burton in the 1970s to describe partial denervation of the facet joints.

Percutaneous Radio-Frequency Facet Nerve Blocks (PRFFNB)– Term used by Burton.  Although unwieldy, this verbage is correct. To be more specific the medial branch of the articular nerve should be identified.

Percutaneous Radiofrequency Medial Branch Nerve Ablation is the more specific term and is being used more at the present time..

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